EMPIAR-12167 - Dissecting human monoclonal antibody responses from mRNA- and protein-based booster vaccinations against XBB.1.5 SARS-CoV-2 [6112 micrographs in MRC format]

EMPIAR-12167

Dissecting human monoclonal antibody responses from mRNA- and protein-based booster vaccinations against XBB.1.5 SARS-CoV-2 [6112 micrographs in MRC format]

Publication:

Mapping of human monoclonal antibody responses to XBB.1.5 COVID-19 monovalent vaccines: a B cell analysis

Fantin RF, Clark JJ, Cohn H, Jaiswal D, Bozarth B, Rao V, Civljak A, Lobo I, Nardulli JR, Srivastava K, Yong JS, Andreata-Santos R, Bushfield K, Lee ES, Singh G, Kleinstein SH, Krammer F, Simon V, Bajic G, Coelho CH

The Lancet. Microbe 6 (2025)

PMID: 40456237

DOI: 10.1016/j.lanmic.2025.101103

Related EMDB entry:

EMD-45443

Deposited:

2024-07-02

Released:

2026-03-20

Last modified:

2026-03-20

Imageset size:

536.67 GB

Imageset DOI:

10.6019/EMPIAR-12167

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Aligned micrographs of SARS-CoV-2 Hexapro Spike with M39 Fab

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

6112

Image size:

(5760, 4092)

Pixel type:

UNSIGNED 32 BIT INTEGER

Pixel spacing:

(None, None)

Details:

---

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)