Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a tetrameric form [17529 multi-frame micrographs composed of 75 frames each in TIFF format]
The micrographs are the average, without any realigment, of 75 raw movie frames (accumulating 65 electron per squared Angstrom in a 1.5 second exposure). All micrographs tilted at 20 degree