EMPIAR-11721 - Cryo-EM structure of human DNA polymerase alpha-primase at handover [13261 multi-frame micrographs composed of 45 frames each in TIFF format]

EMPIAR-11721

Cryo-EM structure of human DNA polymerase alpha-primase at handover [13261 multi-frame micrographs composed of 45 frames each in TIFF format]

Publication:

CryoEM insights into RNA primer synthesis by the human primosome

Yin Z, Kilkenny ML, Ker DS, Pellegrini L

(---)

Related EMDB entry:

EMD-17824

Deposited:

2023-08-09

Released:

2024-06-27

Last modified:

2024-06-27

Imageset size:

3.26 TB

Imageset DOI:

10.6019/EMPIAR-11721

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of human DNA polymerase alpha-primase

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

13261

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.066, 1.066)

Details:

Micrographs were imaged using Gatan K3 camera, each with 45 movie frames using the FEI EPU software with aberration-free image shift. The calibrated pixel size was 1.066 Å, and the total electron dose was 53.67 electrons Å-2 for each micrograph.

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)