Insights from aquaporin structures into drug-resistant sleeping sickness

Mutusevicius M, Corey RA, Gragera M, Yamashita K, Sprenger T, Ungogo MA, Blaza JM, Castro-Hartmann P, Chirgadze DY, Vedithi SC, Afanasyev P, Melero R, Warshamanage R, Gusach A, Carazo JM, Carrington M, Blundell TM, Murshudov G, Stansfeld P, Sansom M, De Koning HP, Tate CG, Weyand SN

eLife RP107460 (2025)

Movies (Export/Images-Disc1/GridSquare_*/Data/FoilHole_*.mrc) in this entry were compressed to TIFF
by EMPIAR Japan to save space and bandwidth.
The compression is lossless in that all pixel intensities remain exactly the same after decompression.
However, some metadata in the MRC header were lost.
The original files before compression are available from EMPIAR EBI.

Compression was carried out by separating (“un-normalizing”) the gain.
The details of the method are described in
https://relion.readthedocs.io/en/release-3.1/Reference/MovieCompression.html#gain-normalised-movies.

Please apply the gain reference (Export/Images-Disc1/gain-reference.mrc) during processing.

PDBj discovered that this entry contained one RSYNC temporary file
(Export/Images-Disc1/GridSquare_7402420/Data/.FoilHole_7409440_Data_7416445_7416446_20190210_1558-136921.mrc.0u7lsa)
and removed it.

Original size:   9,089,188,178 kilobytes
Compressed size: 1,014,695,568 kilobytes