EMPIAR-11402 - PKA-phosphorylated CPVT variant human ryanodine receptor type 2 R2474S in the presence of Rycal ARM210 - RyR2-R2474S + ARM210 [11749 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-11402

PKA-phosphorylated CPVT variant human ryanodine receptor type 2 R2474S in the presence of Rycal ARM210 - RyR2-R2474S + ARM210 [11749 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment

Miotto MC, Weninger G, Dridi H, Yuan Q, Liu Y, Wronska A, Melville Z, Sittenfeld L, Reiken S, Marks AR

Science advances 8 (2022)

PMID: 35857850

DOI: 10.1126/sciadv.abo1272

Related EMDB entry:

EMD-26412 EMD-26410

Deposited:

2023-01-30

Released:

2023-02-08

Last modified:

2023-02-08

Imageset size:

2.38 TB

Imageset DOI:

10.6019/EMPIAR-11402

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. PKA-phosphorylated CPVT variant human ryanodine receptor type 2 R2474S in the presence of Rycal ARM210 - RyR2-R2474S + ARM210

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

11749

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.83, 0.83)

Details:

Reference: references/21aug04b_04142229_01_4092x5760_norm_0.mrc (must invert in Y).

Files:

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Citations

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CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

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See all citations

Protein Data Bank Japan News

[2026-07-01]

288件のPDBエントリーが新たに公開されました。（2026-07-01付）