EMPIAR-11297 - Cryo-EM movies of the human α1β3γ2 GABA<sub>A</sub> receptor in a lipid bilayer bound to bicuculline [988 multi-frame micrographs composed of 75 frames each in TIFF format]

EMPIAR-11297

Cryo-EM movies of the human α1β3γ2 GABA_A receptor in a lipid bilayer bound to bicuculline [988 multi-frame micrographs composed of 75 frames each in TIFF format]

Publication:

GABA_A receptor signalling mechanisms revealed by structural pharmacology

Masiulis S, Desai R, Uchański T, Serna Martin I, Laverty D, Karia D, Malinauskas T, Zivanov J, Pardon E, Kotecha A, Steyaert J, Miller KW, Aricescu AR

Nature 565 (2019) 454-459

PMID: 30602790

DOI: 10.1038/s41586-018-0832-5

Related EMDB entry:

EMD-0280

Deposited:

2022-06-30

Released:

2022-11-15

Last modified:

2023-02-08

Imageset size:

1.23 TB

Imageset DOI:

10.6019/EMPIAR-11297

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Cryo-EM movies of the human α1β3γ2 GABAA receptor in a lipid bilayer bound to bicuculline

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

988

Image size:

(4096, 4096)

Pixel type:

SIGNED 16 BIT INTEGER

Pixel spacing:

(1.07, 1.07)

Details:

---

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)