EMPIAR-10730 - AL amyloid fibril from a glycosylated lambda 1 light chain [3032 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-10730

AL amyloid fibril from a glycosylated lambda 1 light chain [3032 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Role of mutations and post-translational modifications in systemic AL amyloidosis studied by cryo-EM

Radamaker L, Karimi-Farsijani S, Andreotti G, Baur J, Neumann M, Gührs KH, Schreiner S, Berghaus N, Motika R, Haupt C, Walther P, Schmidt V, Huhn S, Hegenbart U, Schönland SO, Wiese S, Read C, Schmidt M, Fändrich M

Nature Communications 12 (2021)

PMID: 34741031

DOI: 10.1038/s41467-021-26553-9

Related EMDB entry:

EMD-12570

Deposited:

2020-06-30

Released:

2021-11-09

Last modified:

2021-11-09

Imageset size:

495.94 GB

Imageset DOI:

10.6019/EMPIAR-10730

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of AL amyloidosis extracted ex vivo amyloid fibrils patient FOR001

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

3032

Image size:

(3838, 3710)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(1.01980390272, 1.01980390272)

Details:

---

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)