The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure [4919 multi-frame micrographs composed of 30 frames each in TIFF format]
Publication:
The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure
Boyer DR, Li B, Sun C, Fan W, Zhou K, Hughes MP, Sawaya MR, Jiang L, Eisenberg DS
Proceedings of the National Academy of Sciences of the United States of America117 (2020) 3592-3602
K2 super-resolution movies. 1.2 e/A^2/frame. 5 frame/second. Cs 2.7. 300 keV. Spot size 7. C2 Aperture 50 um. Gain does not need to be flipped. Coords are start/end only following eman2 helixboxer convention.
