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Electron Microscopy Public Image Archive

EMPIAR-10243
Cryo-EM reconstruction of heparin-induced 2N4R tau filaments [multiple data sets in MRC and TIFF formats]
Publication:

Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases

Zhang W., Falcon B., Murzin A.G., Fan J, Crowther R.A., Goedert M., Scheres S.H.W.

eLife 8 (2019)

PMID: 30720432

Related EMDB entry:
EMD-4563 EMD-4565 EMD-4564
Deposited:
2019-01-23
Released:
2019-03-22
Last modified:
2019-03-22
Imageset size:
446.30 GB
Imageset DOI:
10.6019/EMPIAR-10243
Experimental metadata:
Download xml json
Contains:
  • micrographs - single frame
  • micrographs - multiframe
Image Sets
1. Aligned micrographs
Category:
micrographs - single frame
Image format:
MRC
No. of images or tilt series:
717
Image size:
(4096, 4096)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(1.38, 1.38)
Details:
Aligned and dose-weighted sums.
Files:
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2. Raw movies
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
717
Image size:
(4096, 4096)
Pixel type:
UNSIGNED 16 BIT INTEGER
Pixel spacing:
(1.38, 1.38)
Details:
Raw movies. The dose rate is 1.6 electrons / A^2 / frame.
Files:
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Citations
AlignPCA-2D: PCA-reduced Euclidean vector alignment for 2D classification in cryo-EM.
Ramírez-Aportela E, Zarrabeitia OL, Fonseca YC, Ceska T, Subramaniam S, Carazo JM, Sorzano COS. (2026)
A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.
Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)
Helical reconstruction of amyloids in cryoSPARC.
Schaefer JH, O'Neill RT, Donnelly JP, Powers ET, Kelly JW, Lander GC. (2026)
An unattended image-processing pipeline for on-the-fly quality assessment and 3D exploration in cryo-EM.
Marchán Torres D, Conesa P, Garcia A, Iceta M, Broche L, Gragera M, Linares R, Kwong HS, Chichón FJ, Svensson O, Arranz R, Effantin G, Kandiah E, Carazo JM, Sorzano COS. (2026)
CryoFSL: an annotation-efficient, few-shot learning framework for robust protein particle picking in cryo-electron microscopy micrographs.
Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)
prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.
He L, Bartesaghi A. (2026)
CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.
Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)
Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.
Kong L, Zottig X, Elferich J, Grigorieff N. (2026)
CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.
Gyawali R, Dhakal A, Wang L, Cheng J. (2026)
Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.
Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)
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