EMPIAR-14002
Single-particle cryo-EM dataset of the Human intron-lariat spliceosome–Aquarius (ILSAQR) [multiple data sets in MRC format]
Publication:

Mechanism of spliceosome termination

Boreikaite V, Faraway R, Vorländer MK, Phillips AW, Opitz L, Wanke M, Yakoub G, Raffl G, Fin L, González-Prieto R, Luijsterburg MS, Ameres SL, Plaschka C

Nature (2026)

Deposited:
2026-09-21
Released:
2026-11-09
Last modified:
2026-11-09
Imageset size:
3.26 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - single frame
1. Human ILSAQR dataset 1 dose-weighted micrographs
Category:
micrographs - single frame
Image format:
MRC
No. of images or tilt series:
26091
Image size:
(4096, 4096)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(0.951, 0.951)
Details:
Processed dose-weighted single-frame micrographs generated from 40-frame EER movies acquired on a Titan Krios G4 with a Falcon 4i detector at 300 kV, Cs 2.7 mm, total exposure 40 e-/A^2 and nominal defocus -1.0 to -2.5 um.
Files:
Loading...
2. Human ILSAQR dataset 2 dose-weighted micrographs
Category:
micrographs - single frame
Image format:
MRC
No. of images or tilt series:
27327
Image size:
(4096, 4096)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(0.951, 0.951)
Details:
Processed dose-weighted single-frame micrographs generated from 40-frame EER movies acquired on a Titan Krios G4 with a Falcon 4i detector at 300 kV, Cs 2.7 mm, total exposure 40 e-/A^2 and nominal defocus -1.0 to -2.5 um. Supplementary RELION STAR files are included for EMD-54467 to EMD-54477 and use CryoSPARC particle counts; Map 8 is named TFIP11-GCFC2. Particle stacks are not deposited.
Files:
Loading...
Cheng Y, He B, Zeng Q, Zhang F, Han R. (2026)
Kim K, Li H, Yuan Q, Melville Z, Zalk R, des Georges A, Frank J, Hendrickson WA, Marks AR, Clarke OB. (2026)
Burton Smith RN, Murata K. (2026)
Watanabe R, Lee EB. (2026)
Mikirtumov V, Golusik S, Huo R, Sprink T, Balyschew N, Yang W, Diebolder C, Yuan S, Kotecha A, Kudryashev M. (2026)
Sun Y, Zhao J, Xu N, Wang L, Ding W, Li M. (2026)
Marchán Torres D, Conesa P, Garcia A, Iceta M, Broche L, Gragera M, Linares R, Kwong HS, Chichón FJ, Svensson O, Arranz R, Effantin G, Kandiah E, Carazo JM, Sorzano COS. (2026)
Li F, Dong H, Tang S, Wang X, Zhang C, Ji C, Han R, Zhang F, Wan X. (2026)
So-Last MGF, Burt A, Hale T, Allegretti M. (2026)
Liu J, Schäfer S, Lehnung S, Baumann LM, Mühlberg L, Steiner C, Schreiber M, Linder M, Welsch S, Liu F, Bogdanow B, Krijnse Locker J, Turoňová B. (2026)
Internal Server Error