EMPIAR-13973 - 2026 CAHRA Challenge 1) Compositional Heterogeneity [5200 multi-frame micrographs composed of 945 frames each in EER format]

EMPIAR-13973

2026 CAHRA Challenge 1) Compositional Heterogeneity [5200 multi-frame micrographs composed of 945 frames each in EER format]

Publication:

The CAHRA Challenge: A Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms

Feathers JR, Zhong ED, Heeter RC, Woollard G, Hanson SM, Cossio P, Greer JAT, Burnley T

(---)

DOI: 10.64898/2026.09.15.751515

Related EMDB entry:

Deposited:

2026-08-26

Released:

2026-10-07

Last modified:

2026-10-07

Imageset size:

9.62 TB

Imageset DOI:

10.6019/EMPIAR-13973

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multiframe movies in EER format

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

5200

Image size:

(4096, 4096)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.01, 1.01)

Details:

Particle coordinates and reference labels provided in source.star

Files:

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Citations

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CryoMV: Structure-Prior-Guided Modeling and Real-Particle Validation of Continuous Conformational Transitions in Cryo-EM

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Marchán Torres D, Conesa P, Garcia A, Iceta M, Broche L, Gragera M, Linares R, Kwong HS, Chichón FJ, Svensson O, Arranz R, Effantin G, Kandiah E, Carazo JM, Sorzano COS. (2026)

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A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

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Helical reconstruction of amyloids in cryoSPARC.

Schaefer JH, O'Neill RT, Donnelly JP, Powers ET, Kelly JW, Lander GC. (2026)

CryoFSL: an annotation-efficient, few-shot learning framework for robust protein particle picking in cryo-electron microscopy micrographs.

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Protein Data Bank Japan News

[2026-10-07]

308 new PDB entries have been released on 2026-10-07.