EMPIAR-13570 - Cryo Electron Microscopy micrographs of MRP2 bound to Leukotriene C4 [18196 multi-frame micrographs composed of 36 frames each in EER format]

EMPIAR-13570

Cryo Electron Microscopy micrographs of MRP2 bound to Leukotriene C4 [18196 multi-frame micrographs composed of 36 frames each in EER format]

Publication:

Structural basis for the transport and regulation mechanism of the multidrug resistance-associated protein 2

Koide EK, Pietz HLP, Beltran JB, Chen JC

Nature Communications 484 (2025)

PMID: 39779684

DOI: 10.1038/s41467-024-55810-w

Related EMDB entry:

EMD-45099

Deposited:

2025-07-21

Released:

2026-06-04

Last modified:

2026-06-04

Imageset size:

9.32 TB

Imageset DOI:

10.6019/EMPIAR-13570

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of the multidrug resistance-associated protein 2 (MRP2) bound to Leukotriene C4(LTC4)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

18196

Image size:

(4096, 4096)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(0.743, 0.743)

Details:

This dataset contains raw uncorrected movies. The pixel size is 0.743 Angstrom. Gain reference (20230821_113654_EER_GainReference.gain) is included in the same folder.

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

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Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

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Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)