EMPIAR-13466 - CryoEM reconstruction of coxsackievirus B1 virus-like particle with VP4 deletion [8020 multi-frame micrographs composed of 40 frames each in EER format]

EMPIAR-13466

CryoEM reconstruction of coxsackievirus B1 virus-like particle with VP4 deletion [8020 multi-frame micrographs composed of 40 frames each in EER format]

Publication:

Coxsackie B1 virus-like particle that lacks VP4 protein demonstrates improved vaccine scalability, stability and immunogenicity

Soppela S, Kyrolainen HM, Levanova AA, Nekoua M, Gonzalez-Rodríguez M, Lehto H, Ahmad KLL, Gurianov S, Hytönen VP, Laitinen OH, Junttila IS, Hober D, Butcher SJ, Hankaniemi MM

Journal of Biomedical Science 33 (2026)

DOI: 10.1186/s12929-026-01229-y

Related EMDB entry:

EMD-56033

Deposited:

2025-12-30

Released:

2026-05-13

Last modified:

2026-05-13

Imageset size:

4.86 TB

Imageset DOI:

10.6019/EMPIAR-13466

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. CVB1 Delta VP4 VLP

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

8020

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(None, None)

Details:

---

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

Dual site targeting of the bacterial 70S ribosome by tetracyclines.

Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)