EMPIAR-13176 - Single-particle cryo-EM data of the ternary complex of ReChb - crRNA - target dsDNA [43778 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-13176

Single-particle cryo-EM data of the ternary complex of ReChb - crRNA - target dsDNA [43778 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection

Jabalera Y, Tascón I, Samperio S, López-Alonso JP, Gonzalez-Lopez M, Aransay AM, Abascal-Palacios G, Beisel CL, Ubarretxena-Belandia I, Perez-Jimenez R

Nature biotechnology 43 (2024) 1663-1672

PMID: 39482449

DOI: 10.1038/s41587-024-02461-3

Related EMDB entry:

EMD-18693

Deposited:

2025-12-15

Released:

2026-01-11

Last modified:

2026-01-11

Imageset size:

13.08 TB

Imageset DOI:

10.6019/EMPIAR-13176

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of the ternary complex of ReChb - crRNA - target dsDNA

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

43778

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.8238, 0.8238)

Details:

---

Files:

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Citations

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)