EMPIAR-13117 - Cryo-EM of connexin-46/50 in DMPC nanodiscs at low pH (Collection #1) [7071 multi-frame micrographs composed of 55 frames each in TIFF format]

EMPIAR-13117

Cryo-EM of connexin-46/50 in DMPC nanodiscs at low pH (Collection #1) [7071 multi-frame micrographs composed of 55 frames each in TIFF format]

Publication:

Reversible lipid-mediated pH-gating of connexin-46/50 by cryo-EM

Jarodsky JM, Myers JB, Reichow SL

Nature communications 17 (2026)

PMID: 41526355

DOI: 10.1038/s41467-026-68311-9

Related EMDB entry:

EMD-73942 EMD-73957 EMD-7396

Deposited:

2025-11-20

Released:

2026-04-07

Last modified:

2026-04-07

Imageset size:

2.75 TB

Imageset DOI:

10.6019/EMPIAR-13117

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned mutli-frame raw frames of Connexin-46/50 in DMPC nanodiscs at low pH

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

7071

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.4008, 0.4008)

Details:

---

Files:

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Citations

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)