EMPIAR-13116 - Cryo-EM of Connexin-46/50 in DMPC nanodiscs returned to neutral pH (Collection #6) [6140 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-13116

Cryo-EM of Connexin-46/50 in DMPC nanodiscs returned to neutral pH (Collection #6) [6140 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Reversible lipid-mediated pH-gating of connexin-46/50 by cryo-EM

Jarodsky JM, Myers JB, Reichow SL

Nature communications 17 (2026)

PMID: 41526355

DOI: 10.1038/s41467-026-68311-9

Related EMDB entry:

EMD-73885 EMD-73900 EMD-73896

Deposited:

2025-11-15

Released:

2026-04-07

Last modified:

2026-04-07

Imageset size:

2.17 TB

Imageset DOI:

10.6019/EMPIAR-13116

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned mutli-frame raw micrographs of Connexin-46/50 in DMPC nanodiscs at neutral pH

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

6140

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.411, 0.411)

Details:

---

Files:

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Citations

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

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He L, Bartesaghi A. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)