EMPIAR-13111 - Cryo-EM structure of the prostaglandin D2 receptor 1 (DP1) complex in inactive and active states [multiple data sets in MRC and TIFF formats]

EMPIAR-13111

Cryo-EM structure of the prostaglandin D2 receptor 1 (DP1) complex in inactive and active states [multiple data sets in MRC and TIFF formats]

Publication:

Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1

Davoudinasab B, Raskovalov A, Lee W, Kim D, Kim H, Lam JH, Han GW, Katritch V, Cherezov V

Nature Communications (2025)

PMID: 41062467

DOI: 10.1038/s41467-025-64002-z

Related EMDB entry:

EMD-47950 EMD-48122 EMD-47802 EMD-43839

Deposited:

2025-08-15

Released:

2025-12-19

Last modified:

2025-12-19

Imageset size:

6.04 TB

Imageset DOI:

10.6019/EMPIAR-13111

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Cryo-EM structure of the ONO2550289-bound prostaglandin D2 receptor 1 (DP1)-bRIL-Fab complex

Category:

micrographs - multiframe

Image format:

MRC

No. of images or tilt series:

5927

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.86, 0.86)

Details:

Motion corrected dataset

Files:

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2. Cryo-EM structure of the ONO3030297-bound prostaglandin D2 receptor 1 (DP1)-bRIL-Fab complex

Category:

micrographs - multiframe

Image format:

MRC

No. of images or tilt series:

5747

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.86, 0.86)

Details:

Motion corrected dataset

Files:

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3. Cryo-EM structure of the BW245C-bound prostaglandin D2 receptor 1 (DP1)-Gs-Nb35 complex

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

9476

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.84, 0.84)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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4. Cryo-EM structure of the PGD2-bound prostaglandin D2 receptor 1 (DP1)-Gs-Nb35 complex

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

10096

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.84, 0.84)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

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Citations

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CryoEMNet driven symmetry-aware molecular reconstruction through deep learning enhanced electron microscopy.

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