EMPIAR-13002 - Cryo Electron Microscopy of hIAPP A25P, S28P and S29P mutants [multiple data sets in TIFF and EER formats]

EMPIAR-13002

Cryo Electron Microscopy of hIAPP A25P, S28P and S29P mutants [multiple data sets in TIFF and EER formats]

Publication:

Cryo-EM exposes diverse polymorphism in IAPP mutants to guide the rational design of peptide-based therapeutics

Ooi SA, Valli D, Maj M

Journal of Molecular Biology 437 (2025)

PMID: 40850490

DOI: 10.1016/j.jmb.2025.169405

Related EMDB entry:

EMD-18671 EMD-19354 EMD-19353 EMD-18673 EMD-18441 EMD-18672

Deposited:

2025-09-04

Released:

2025-11-18

Last modified:

2025-11-18

Imageset size:

16.23 TB

Imageset DOI:

10.6019/EMPIAR-13002

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Multiframe micrographs of hIAPP A25P mutant

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

27951

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.8566, 0.8566)

Details:

---

Files:

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2. Multiframe micrographs of hIAPP A25P mutant

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

12428

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.704, 0.704)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

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3. Multiframe micrographs of hIAPP A25P mutant

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

12180

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.821, 0.821)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

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Citations

GTpick: A deep neural network for Cryo-EM particle detection.

Ni S, Yang C, Liu Y, Zhang Y, Shi Y, Qian A, Kong R, Chang S. (2025)

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles

Kim K, Li H, Clarke OB. (2025)

CLEM-Reg: an automated point cloud-based registration algorithm for volume correlative light and electron microscopy.

Krentzel D, Elphick M, Domart MC, Peddie CJ, Laine RF, Shand C, Henriques R, Collinson LM, Jones ML. (2025)

PERC: a suite of software tools for the curation of cryoEM data with application to simulation, modeling and machine learning.

Costa-Gomes B, Greer J, Juraschko N, Parkhurst J, Mirecka J, Famili M, Rangel-Smith C, Strickson O, Lowe A, Basham M, Burnley T. (2025)

CryoEMNet driven symmetry-aware molecular reconstruction through deep learning enhanced electron microscopy.

Arora S, Pan SH, Kumar S, Singh SK, Chauhan U, Alhalabi W, Arya V, Alsulami BS, Hsu CH, Chui KT, Gupta BB. (2025)

Self-supervised learning for generalizable particle picking in cryo-EM micrographs.

Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)

Localization of macromolecules in crowded cellular cryo-electron tomograms from extremely sparse labels.

Uddin MR, Ahmed AY, Tabib HMS, Tahmid MT, Alam MZU, Freyberg Z, Xu M. (2025)

Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase.

Wu K, Wang Z, Yao D, Li S, Wang X, Zhang Y, Cao M, Shen Y, Xing S, Wu J, Lei M, Lan P. (2025)

Conserved hydrophilic checkpoints tune FocA-mediated formate:H<sup>+</sup> symport.

Tüting C, Janson K, Kammel M, Ihling C, Lorenz J, Kyrilis FL, Hamdi F, Erdmann C, Sinz A, Sawers RG, Kastritis PL. (2025)

Icecream: High-Fidelity Equivariant Cryo-Electron Tomography

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2025)

See all citations

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