EMPIAR-12941 - Human Argonaute1 F180 Deletion with BS3 [3015 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-12941

Human Argonaute1 F180 Deletion with BS3 [3015 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Neurodevelopmental disorder-linked Argonaute mutations permit delayed RISC formation and unusual shortening of miRNAs by 3'→5' trimming

Savidge A, Zhang H, Annasaheb Adhav V, Kehling AC, Sim G, Shen Z, Fu TM, Nakanishi K

Proceedings of the National Academy of Sciences of the United States of America 122 (2025)

PMID: 41237208

DOI: 10.1073/pnas.2524644122

Related EMDB entry:

EMD-72192

Deposited:

2025-08-18

Released:

2026-05-22

Last modified:

2026-05-22

Imageset size:

1.46 TB

Imageset DOI:

10.6019/EMPIAR-12941

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned unprocessed movies of AGO1 WT

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

3015

Image size:

(8184, 11520)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(0.448, 0.448)

Details:

Data analysis used the TIFF stacks under the name "*fractions.tiff".

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

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Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

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CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

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Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)