EMPIAR-12913
Single particle Cryo-EM structure of the Pdr5 drug resistance transporter [multiple data sets in TIFF format]
Publication:

Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5

Harris A, Wagner M, Du D, Raschka S, Nentwig LM, Gohlke H, Smits SHJ, Luisi BF, Schmitt L

Nature communications 12 (2021)

PMID: 34489436

Related EMDB entry:
Deposited:
2025-07-25
Released:
2025-12-07
Last modified:
2025-12-07
Imageset size:
3.83 TB
Imageset DOI:
Experimental metadata:
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Contains:
  • micrographs - multiframe
1. Unaligned multi frame micrographs of Pdr5 bound to ADP.
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
3415
Image size:
(None, None)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(None, None)
Details:
Pdr5 sample with added ATP yielded a map containing the hydrolysed nucleotide ADP in the canonical and ATP in the inactive site, referred to in the paper as ADP-Pdr5.
Files:
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2. Unaligned multi frame micrographs of Pdr5 bound to R6G.
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
3604
Image size:
(None, None)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(None, None)
Details:
Pdr5 with added ATP and transport substrate rhodamine 6 G (R6G).
Files:
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3. Unaligned multi frame micrographs of Pdr5 bound to ADP.
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
8370
Image size:
(None, None)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(None, None)
Details:
Pdr5 with added ATP and sodium orthovanadate (Vi).
Files:
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