EMPIAR-12899 - Cryo electron micrographs of RyR2-R420W with calcium [7490 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-12899

Cryo electron micrographs of RyR2-R420W with calcium [7490 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders

Miotto MC, Reiken S, Wronska A, Yuan Q, Dridi H, Liu Y, Weninger G, Tchagou C, Marks AR

Nature communications 15 (2024)

PMID: 39278969

DOI: 10.1038/s41467-024-51791-y

Related EMDB entry:

EMD-42764 EMD-42765

Deposited:

2025-07-28

Released:

2025-09-05

Last modified:

2025-09-05

Imageset size:

1.64 TB

Imageset DOI:

10.6019/EMPIAR-12899

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Cryo electron micrographs of RyR2-R420W with calcium

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

7490

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.83, 0.83)

Details:

Reference: 22apr12a_14115349_01_4092x5760_norm_0.mrc (must invert in Y).

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)