EMPIAR-12815 - Single particle cryo-EM dataset of cardiac immunoglobulin lambda-6 light-chain AL-224L [10309 multi-frame micrographs composed of 936 frames each in EER format]

EMPIAR-12815

Single particle cryo-EM dataset of cardiac immunoglobulin lambda-6 light-chain AL-224L [10309 multi-frame micrographs composed of 936 frames each in EER format]

Publication:

Cryo-EM of cardiac AL-224L amyloid reveals shared features in λ6 light chain fibril folds

Hicks CW, Prokaeva T, Spencer B, Jayaraman S, Huda N, Wong S, Chen H, Sanchorawala V, Lavatelli F, Gursky O

bioRxiv (2025)

DOI: 10.1101/2025.06.25.661559

Related EMDB entry:

EMD-70557

Deposited:

2025-05-12

Released:

2026-01-05

Last modified:

2026-01-05

Imageset size:

4.39 TB

Imageset DOI:

10.6019/EMPIAR-12815

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of cardiac lambda-6 light chain amyloid AL-224L fibrils

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

10309

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.9, 0.9)

Details:

---

Files:

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Citations

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Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

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He L, Bartesaghi A. (2026)

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Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

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Jones HN, Deshmukh A, Pande K. (2026)

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CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

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Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)

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