EMPIAR-12815 - Single particle cryo-EM dataset of cardiac immunoglobulin lambda-6 light-chain AL-224L [10309 multi-frame micrographs composed of 936 frames each in EER format]

EMPIAR-12815

Single particle cryo-EM dataset of cardiac immunoglobulin lambda-6 light-chain AL-224L [10309 multi-frame micrographs composed of 936 frames each in EER format]

Publication:

Cryo-EM of cardiac AL-224L amyloid reveals shared features in λ6 light chain fibril folds

Hicks CW, Prokaeva T, Spencer B, Jayaraman S, Huda N, Wong S, Chen H, Sanchorawala V, Lavatelli F, Gursky O

bioRxiv (2025)

DOI: 10.1101/2025.06.25.661559

Related EMDB entry:

EMD-70557

Deposited:

2025-05-12

Released:

2026-01-05

Last modified:

2026-01-05

Imageset size:

4.39 TB

Imageset DOI:

10.6019/EMPIAR-12815

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of cardiac lambda-6 light chain amyloid AL-224L fibrils

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

10309

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.9, 0.9)

Details:

---

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)