EMPIAR-12702 - Single particle Cryo EM of the C-terminal half LRRK2 bound to MLi-2 [5189 multi-frame micrographs composed of 40 frames each in MRC format]

EMPIAR-12702

Single particle Cryo EM of the C-terminal half LRRK2 bound to MLi-2 [5189 multi-frame micrographs composed of 40 frames each in MRC format]

Publication:

Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures

Sanz Murillo M, Villagran Suarez A, Dederer V, Chatterjee D, Alegrio Louro J, Knapp S, Mathea S, Leschziner AE

Science advances 9 (2023)

PMID: 38039358

DOI: 10.1126/sciadv.adk6191

Related EMDB entry:

EMD-41728

Deposited:

2025-04-10

Released:

2025-10-09

Last modified:

2025-10-09

Imageset size:

1.06 TB

Imageset DOI:

10.6019/EMPIAR-12702

Experimental metadata:

Download xml json

Compressed by PDBj:

Image formats and pixel types shown below are those of the original, non-compressed files.

--- file not found ---

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multiframe micrographs

Category:

micrographs - multiframe

Image format:

MRC

No. of images or tilt series:

5189

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.822, 0.822)

Details:

---

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Citations

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Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

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He L, Bartesaghi A. (2026)

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Jones HN, Deshmukh A, Pande K. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

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CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)

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