EMPIAR-12622 - Cryo-EM structure of human MPC in complex with AKOS005153046 [16536 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-12622

Cryo-EM structure of human MPC in complex with AKOS005153046 [16536 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Structure of mitochondrial pyruvate carrier and its inhibition mechanism

He Z, Zhang J, Xu Y, Fine EJ, Suomivuori CM, Dror RO, Feng L

Nature (2025)

PMID: 40044865

DOI: 10.1038/s41586-025-08667-y

Related EMDB entry:

EMD-48445

Deposited:

2025-03-04

Released:

2025-06-13

Last modified:

2025-06-13

Imageset size:

6.09 TB

Imageset DOI:

10.6019/EMPIAR-12622

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. unaligned multi-frame micrographs of human MPC in complex with AKOS005153046

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

16536

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

---

Files:

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Citations

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)