EMPIAR-12530 - Cryo-EM structure of hydroxychloroquine-bound human SLC19A3 in inward-open state [9492 multi-frame micrographs composed of 58 frames each in TIFF format]

EMPIAR-12530

Cryo-EM structure of hydroxychloroquine-bound human SLC19A3 in inward-open state [9492 multi-frame micrographs composed of 58 frames each in TIFF format]

Publication:

Structural basis of thiamine transport and drug recognition by SLC19A3

Gabriel FG

Nature Communications 15 (2024)

PMID: 39358356

DOI: 10.1038/s41467-024-52872-8

Related EMDB entry:

EMD-19753

Deposited:

2025-01-16

Released:

2025-07-25

Last modified:

2025-07-25

Imageset size:

2.64 TB

Imageset DOI:

10.6019/EMPIAR-12530

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Multiframe micrographs of hydroxychloroquine-bound human SLC19A3 in complex with Nb3.3

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

9492

Image size:

(4096, 4096)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.57, 0.57)

Details:

---

Files:

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)