EMPIAR-12199
Full-length mouse 5-HT3A receptor in complex with SMP100, pre-activated and open-like [multiple data sets in TIFF format]
Publication:

Structural basis for partial agonism in 5-HT3A receptors

Felt K, Stauffer M, Salas-Estrada L, Guzzo PR, Xie D, Huang J, Filizola M, Chakrapani S

Nature structural & molecular biology 31 (2024) 598-609

PMID: 38177669

Related EMDB entry:
Deposited:
2024-07-15
Released:
2024-08-28
Last modified:
2024-08-28
Imageset size:
6.31 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Raw movies, 5-HT3A + SMP100, one of two datasets
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
5030
Image size:
(11520, 8184)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(1.1, 1.1)
Details:
Raw movies of 5-HT3AR in complex with 3x molar excess SMP100. Collected on titan krios and k3 camera. 81,000x magnification, super-resolution (import with 0.55 angstrom pixel size, 2x bin in Motioncorr), around 1 electron dose per frame. Dataset 1 of 2.
Files:
Loading...
2. Raw movies, 5-HT3A + SMP100, two of two datasets
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
5625
Image size:
(11520, 8184)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(1.1, 1.1)
Details:
Raw movies of 5-HT3AR in complex with 3x molar excess SMP100. Collected on titan krios and k3 camera. 81,000x magnification, super-resolution (import with 0.55 angstrom pixel size, 2x bin in Motioncorr), around 1 electron dose per frame. Dataset 2 of 2.
Files:
Loading...
Files:
Loading...
Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)
Fan X, Zhang Q, Zhang H, Zhu J, Ju L, Shi Z, Hu M, Bao C. (2024)
Zheng L, Xu J, Wang W, Gao X, Zhao C, Guo W, Sun L, Cheng H, Meng F, Chen B, Sun W, Jia X, Zhou X, Wu K, Liu Z, Ding F, Liu N, Wang HW, Peng H. (2024)