EMPIAR-12012 - Cryo-EM images of alpha-synuclein fibrils «1B» capable of seeding GCI in vivo [multiple data sets in MRC and EER formats]

EMPIAR-12012

Cryo-EM images of alpha-synuclein fibrils «1B» capable of seeding GCI in vivo [multiple data sets in MRC and EER formats]

Publication:

Multiple System Atrophy: Insights from α-Syn Fibril Structure

Burger D, Kashyrina M, Lewis A, De Nuccio F, Mohammed I, de La Seigliere H, van den Heuvel L, Feuillie C, Verchere J, Berbon M, Arotcarena M, Retailleau A, Bezard E, Laferriere F, Loquet A, Bousset L, Baron T, Lofrumento DD, De Giorgi F, Stahlberg H, Ichas F

(---)

Related EMDB entry:

EMD-19986

Deposited:

2024-03-28

Released:

2025-08-13

Last modified:

2025-08-13

Imageset size:

8.83 TB

Imageset DOI:

10.6019/EMPIAR-12012

Experimental metadata:

Download xml json

Contains:

micrographs - single frame
micrographs - multiframe

Image Sets

1. Motion corrected and dose weighted images with Relion 4.0

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

19636

Image size:

(4096, 4096)

Pixel type:

16 BIT FLOAT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

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2. Unaligned raw eer files (subset 1)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

4720

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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3. Unaligned raw eer files (subset 2)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

8272

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

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4. Unaligned raw eer files (subset 3)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

6644

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

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Citations

AlignPCA-2D: PCA-reduced Euclidean vector alignment for 2D classification in cryo-EM.

Ramírez-Aportela E, Zarrabeitia OL, Fonseca YC, Ceska T, Subramaniam S, Carazo JM, Sorzano COS. (2026)

A variational framework with composite sparse regularization for cryo-electron tomography reconstruction.

Yu C, Xu Z, Zeng Q, Wan X, El-Messiry H, Zhang F, Han R. (2026)

Helical reconstruction of amyloids in cryoSPARC.

Schaefer JH, O'Neill RT, Donnelly JP, Powers ET, Kelly JW, Lander GC. (2026)

CryoFSL: an annotation-efficient, few-shot learning framework for robust protein particle picking in cryo-electron microscopy micrographs.

Poudel B, Gyawali R, Dhakal A, Cheng J, Xu D. (2026)

An unattended image-processing pipeline for on-the-fly quality assessment and 3D exploration in cryo-EM.

Marchán Torres D, Conesa P, Garcia A, Iceta M, Broche L, Gragera M, Linares R, Kwong HS, Chichón FJ, Svensson O, Arranz R, Effantin G, Kandiah E, Carazo JM, Sorzano COS. (2026)

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

See all citations

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