EMPIAR-12012 - Cryo-EM images of alpha-synuclein fibrils «1B» capable of seeding GCI in vivo [multiple data sets in MRC and EER formats]

EMPIAR-12012

Cryo-EM images of alpha-synuclein fibrils «1B» capable of seeding GCI in vivo [multiple data sets in MRC and EER formats]

Publication:

Multiple System Atrophy: Insights from α-Syn Fibril Structure

Burger D, Kashyrina M, Lewis A, De Nuccio F, Mohammed I, de La Seigliere H, van den Heuvel L, Feuillie C, Verchere J, Berbon M, Arotcarena M, Retailleau A, Bezard E, Laferriere F, Loquet A, Bousset L, Baron T, Lofrumento DD, De Giorgi F, Stahlberg H, Ichas F

(---)

Related EMDB entry:

EMD-19986

Deposited:

2024-03-28

Released:

2025-08-13

Last modified:

2025-08-13

Imageset size:

8.83 TB

Imageset DOI:

10.6019/EMPIAR-12012

Experimental metadata:

Download xml json

Contains:

micrographs - single frame
micrographs - multiframe

Image Sets

1. Motion corrected and dose weighted images with Relion 4.0

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

19636

Image size:

(4096, 4096)

Pixel type:

16 BIT FLOAT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

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2. Unaligned raw eer files (subset 1)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

4720

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

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3. Unaligned raw eer files (subset 2)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

8272

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

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4. Unaligned raw eer files (subset 3)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

6644

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

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Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model.

Kong L, Zottig X, Elferich J, Grigorieff N. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

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Devarkar SC, Lomakin IB, Wang J, Grada A, Bunick CG. (2026)

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Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

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Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)