EMPIAR-12012 - Cryo-EM images of alpha-synuclein fibrils «1B» capable of seeding GCI in vivo [multiple data sets in MRC and EER formats]

EMPIAR-12012

Cryo-EM images of alpha-synuclein fibrils «1B» capable of seeding GCI in vivo [multiple data sets in MRC and EER formats]

Publication:

Multiple System Atrophy: Insights from α-Syn Fibril Structure

Burger D, Kashyrina M, Lewis A, De Nuccio F, Mohammed I, de La Seigliere H, van den Heuvel L, Feuillie C, Verchere J, Berbon M, Arotcarena M, Retailleau A, Bezard E, Laferriere F, Loquet A, Bousset L, Baron T, Lofrumento DD, De Giorgi F, Stahlberg H, Ichas F

(---)

Related EMDB entry:

EMD-19986

Deposited:

2024-03-28

Released:

2025-08-13

Last modified:

2025-08-13

Imageset size:

8.83 TB

Imageset DOI:

10.6019/EMPIAR-12012

Experimental metadata:

Download xml json

Contains:

micrographs - single frame
micrographs - multiframe

Image Sets

1. Motion corrected and dose weighted images with Relion 4.0

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

19636

Image size:

(4096, 4096)

Pixel type:

16 BIT FLOAT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

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2. Unaligned raw eer files (subset 1)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

4720

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

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Download a list of selected files.

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3. Unaligned raw eer files (subset 2)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

8272

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

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4. Unaligned raw eer files (subset 3)

Category:

micrographs - multiframe

Image format:

EER

No. of images or tilt series:

6644

Image size:

(4096, 4096)

Pixel type:

BIT

Pixel spacing:

(0.66, 0.66)

Details:

---

Files:

This entry cannot be downloaded from PDBj.

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

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Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

Outer membrane protein assembly mediated by BAM-SurA complexes.

Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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