EMPIAR-11870
Single particle Cryo EM of the C-terminal half LRRK2 G2019S mutant bound to GZD-824 [7988 multi-frame micrographs composed of 40 frames each in EER format]
Publication:

Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures

Sanz Murillo M, Villagran Suarez A, Dederer V, Chatterjee D, Alegrio Louro J, Knapp S, Mathea S, Leschziner AE

Science advances 9 (2023)

PMID: 38039358

Related EMDB entry:
Deposited:
2024-01-24
Released:
2024-02-09
Last modified:
2024-02-09
Imageset size:
6.99 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multiframe micrographs
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
7988
Image size:
(None, None)
Pixel type:
UNSIGNED 16 BIT INTEGER
Pixel spacing:
(0.935, 0.935)
Details:
Contains data collected from 1 grids on different days, 03/23/2023 and 03/27/2023
Files:
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Citations

Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS. (2023)
Rigden DJ, Fernández XM. (2023)
Iudin A, Korir PK, Somasundharam S, Weyand S, Cattavitello C, Fonseca N, Salih O, Kleywegt GJ, Patwardhan A. (2023)
Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y. (2023)
Caldwell BJ, Norris AS, Karbowski CF, Wiegand AM, Wysocki VH, Bell CE. (2022)