EMPIAR-11869
Single particle Cryo EM of the LRRK2 I2020T mutant bound to GZD-824 [4102 multi-frame micrographs composed of 40 frames each in EER format]
Publication:

Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures

Sanz Murillo M, Villagran Suarez A, Dederer V, Chatterjee D, Alegrio Louro J, Knapp S, Mathea S, Leschziner AE

Science advances 9 (2023)

PMID: 38039358

Related EMDB entry:
Deposited:
2024-01-23
Released:
2024-02-08
Last modified:
2024-02-08
Imageset size:
4.59 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multiframe micrographs
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
4102
Image size:
(None, None)
Pixel type:
UNSIGNED 16 BIT INTEGER
Pixel spacing:
(0.95, 0.95)
Details:
Contains data collected from 1 grids.
Files:
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Citations

Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS. (2023)
Rigden DJ, Fernández XM. (2023)
Iudin A, Korir PK, Somasundharam S, Weyand S, Cattavitello C, Fonseca N, Salih O, Kleywegt GJ, Patwardhan A. (2023)
Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y. (2023)
Caldwell BJ, Norris AS, Karbowski CF, Wiegand AM, Wysocki VH, Bell CE. (2022)