EMPIAR-11730
ATTRG47E amyloid fibrils from hereditary ATTR amloidosis [12067 multi-frame micrographs composed of 2226 frames each in EER format]
Publication:

Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis

Steinebrei M, Baur J, Pradhan A, Kupfer N, Wiese S, Hegenbart U, Schönland SO, Schmidt M, Fändrich M

Nature communications 14 (2023)

PMID: 37993462

Related EMDB entry:
Deposited:
2023-10-12
Released:
2024-09-03
Last modified:
2024-09-03
Imageset size:
6.82 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame micrographs of ATTRVG47E amyloid fibrils
Category:
micrographs - multiframe
Image format:
EER
No. of images or tilt series:
12067
Image size:
(4096, 4096)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.934, 0.934)
Details:
EMBL Heidelberg (25 November 2021)
IC-Krios1 300kV Cold FEG
SelectrisX Falcon4 10eV slit
Cs=2.7mm, C2aperture=50um, ObjAperture=100um
EFTEM 130K, nanoprobe spot 5, beam=650nm
Counting mode, 1pix=0.934A
9s exposure, EER files saved (2226 raw EER frames)
dose rate ~4e/pix/s at the sample level (~41.63 e/A2 total!)

4 shots per hole, no middle
defocus range -0.90 to -1.80um
Files:
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