Cork-in-bottle mechanism of inhibitor binding to mammalian complex I.

Chung I, Serreli R, Cross JB, Di Francesco ME, Marszalek JR, Hirst J

Science advances 7 (2021)

Movies (FoilHole*.mrc) in this entry were compressed to TIFF by EMPIAR Japan to save space and bandwidth.
The compression is lossless in that all pixel intensities remain exactly the same after decompression.
However, some metadata in the MRC header were lost.
The original files before compression are available from EMPIAR EBI.

Compression was carried out by separating (“un-normalizing”) the gain.
The details of the method are described in
https://relion.readthedocs.io/en/release-3.1/Reference/MovieCompression.html#gain-normalised-movies.

PDBj discovered that the movies were recorded with two gain references.
They were grouped into gain-group1 and gain-group2 subdirectories.
Please apply the gain reference (gain-reference.mrc in each folder) during processing.

Original size:   2,721,260,365 kilobytes
Compressed size:   327,778,511 kilobytes