EMPIAR-11493
5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM) [9617 multi-frame micrographs composed of 50 frames each in TIFF format]
Publication:

Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD

Cao C, Barros-Álvarez X, Zhang S, Kim K, Dämgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Hüttenhain R, Nichols DE, Dror RO, Skiniotis G, Roth BL

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Related EMDB entry:
Deposited:
2022-07-27
Released:
2024-02-09
Last modified:
2024-02-09
Imageset size:
5.05 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame micrographs of 5-HT2B receptor bound to LSD in complex with beta-arrestin1
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
9617
Image size:
(11520, 8184)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.42605, 0.42605)
Details:
3 datasets were merged for this reconstruction. For the three, the micrographs are the average of 50 raw movie frames accumulating 68 electron per squared Angstrom in a 2.5 sec exposure.
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Citations

Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS. (2023)
Rigden DJ, Fernández XM. (2023)
Iudin A, Korir PK, Somasundharam S, Weyand S, Cattavitello C, Fonseca N, Salih O, Kleywegt GJ, Patwardhan A. (2023)
Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y. (2023)
Caldwell BJ, Norris AS, Karbowski CF, Wiegand AM, Wysocki VH, Bell CE. (2022)