EMPIAR-11493 - 5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM) [9617 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-11493

5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM) [9617 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD

Cao C, Barros-Álvarez X, Zhang S, Kim K, Dämgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Hüttenhain R, Nichols DE, Dror RO, Skiniotis G, Roth BL

(---)

DOI: 10.1016/j.neuron.2022.08.006

Related EMDB entry:

EMD-25403

Deposited:

2022-07-27

Released:

2024-02-09

Last modified:

2024-02-09

Imageset size:

5.05 TB

Imageset DOI:

10.6019/EMPIAR-11493

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of 5-HT2B receptor bound to LSD in complex with beta-arrestin1

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

9617

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.42605, 0.42605)

Details:

3 datasets were merged for this reconstruction. For the three, the micrographs are the average of 50 raw movie frames accumulating 68 electron per squared Angstrom in a 2.5 sec exposure.

Files:

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Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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