EMPIAR-11448
5-HT2B receptor bound to LSD in complex with heterotrimeric mini-Gq protein obtained by cryo-electron microscopy (cryoEM) [3916 multi-frame micrographs composed of 57 frames each in TIFF format]
Publication:

Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD

Cao C, Barros-Álvarez X, Zhang S, Kim K, Dämgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Hüttenhain R, Nichols DE, Dror RO, Skiniotis G, Roth BL

Neuron 110 (2022) 3154-3167.e7

PMID: 36087581

Related EMDB entry:
Deposited:
2022-07-02
Released:
2024-02-09
Last modified:
2024-02-09
Imageset size:
2.05 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame micrographs of 5-HT2B receptor bound to LSD in complex with heterotrimeric mini-Gq protein
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
3916
Image size:
(11520, 8184)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.43385, 0.43385)
Details:
The micrographs are the average of 57 raw movie frames accumulating 61.11 electron per squared Angstrom in a 2.5 sec exposure.
Files:
Loading...
Files:
Loading...
Citations

Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS. (2023)
Rigden DJ, Fernández XM. (2023)
Iudin A, Korir PK, Somasundharam S, Weyand S, Cattavitello C, Fonseca N, Salih O, Kleywegt GJ, Patwardhan A. (2023)
Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y. (2023)
Caldwell BJ, Norris AS, Karbowski CF, Wiegand AM, Wysocki VH, Bell CE. (2022)