Insights from aquaporin structures into drug-resistant sleeping sickness
Matusevicius M, Corey RA, Gragera M, Yamashita K, Sprenger T, Ungogo MA, Blaza JM, Castro-Hartmann P, Chirgadze DY, Vedithi SC, Afanasyev P, Melero R, Warshamanage R, Gusach A, Carazo JM, Carrington M, Blundell TM, Murshudov G, Stansfeld P, Sansom M, De Koning HP, Tate CG, Weyand SN
eLife RP107460 (2025)
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Movies (Export/FoilHole*.mrc) in this entry were compressed to TIFF by EMPIAR Japan to save space and bandwidth. The compression is lossless in that all pixel intensities remain exactly the same after decompression. However, some metadata in the MRC header were lost. The original files before compression are available from EMPIAR EBI. Compression was carried out by separating (“un-normalizing”) the gain. The details of the method are described in https://relion.readthedocs.io/en/release-3.1/Reference/MovieCompression.html#gain-normalised-movies. Please apply the gain reference (Export/gain-reference.mrc) during processing. PDBj discovered that this entry contained an ascp binary (`Export/ascp`) and removed it. PDBj also discovered that three movies in `Export/pentamidine` were duplicates of the same files in `Export` and removed them. Original size: 7,257,434,604 kilobytes Compressed size: 788,940,215 kilobytes