EMPIAR-11362
Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism [multiple data sets in TIFF and MRC formats]
Publication:

Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism

Lomakin IB, Devarkar SC, Patel S, Grada A, Bunick CG

Nucleic acids research (2023)

PMID: 36864821

Related EMDB entry:
Deposited:
2022-12-06
Released:
2023-04-11
Last modified:
2023-04-11
Imageset size:
6.16 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
  • picked particles - single frame - processed
  • micrographs - single frame
1. Raw multiframe micrographs for Sarecycline bound 70S Ribosome from C. acnes
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
10765
Image size:
(11520, 8184)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(0.534, 0.534)
Details:
---
Files:
Loading...
2. Extracted particle stack based on Template picking from cryoSPARC
Category:
picked particles - single frame - processed
Image format:
MRC
No. of images or tilt series:
1108852
Image size:
(340, 340)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(1.068, 1.068)
Details:
A stack of 1108852 particles picked from 10,765 motion-corrected micrographs
Files:
Loading...
3. Dose-Weighted Motion Corrected Micrographs for Sarecycline bound 70S Ribosome from C. acnes
Category:
micrographs - single frame
Image format:
MRC
No. of images or tilt series:
10765
Image size:
(5760, 4092)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(1.068, 1.068)
Details:
Dose-weighted motion corrected micrographs using Patch motion correction in cryoSPARC
Files:
Loading...
4. Non-Dose-Weighted Motion Corrected Micrographs for Sarecycline bound 70S Ribosome from C. acnes
Category:
micrographs - single frame
Image format:
MRC
No. of images or tilt series:
10765
Image size:
(5760, 4092)
Pixel type:
32 BIT FLOAT
Pixel spacing:
(1.068, 1.068)
Details:
Non-dose-weighted motion corrected micrographs using Patch motion correction in cryoSPARC
Files:
Loading...
Files:
Loading...

Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS. (2023)
Rigden DJ, Fernández XM. (2023)
Iudin A, Korir PK, Somasundharam S, Weyand S, Cattavitello C, Fonseca N, Salih O, Kleywegt GJ, Patwardhan A. (2023)
Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y. (2023)
Caldwell BJ, Norris AS, Karbowski CF, Wiegand AM, Wysocki VH, Bell CE. (2022)