EMPIAR-10921 - C-terminal half of Leucine Rich Repeat Kinase 1 (LRRK1) [3629 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-10921

C-terminal half of Leucine Rich Repeat Kinase 1 (LRRK1) [3629 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules

Snead DM, Matyszewski M, Dickey AM, Lin YX, Leschziner AE, Reck-Peterson SL

Nature structural & molecular biology 29 (2022) 1196-1207

PMID: 36510024

DOI: 10.1038/s41594-022-00863-y

Related EMDB entry:

EMD-25672

Deposited:

2022-01-08

Released:

2023-01-03

Last modified:

2023-01-03

Imageset size:

1.16 TB

Imageset DOI:

10.6019/EMPIAR-10921

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multi-frame micrographs of the C-terminus of Leucine Rich Repeat Kinase 1 (LRRK1)

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

3629

Image size:

(3710, 3838)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(1.16, 1.16)

Details:

Contains 4 datasets: 19dec11a, 19dec21c, 20sep11a, 21jan18d.
All had the total dose set to 55 e/A-2.
20sep11a was collected with a 20-degree tilt.
Each dataset has different number of frames due to changes in beam strength.
19dec11a: 50 frames
19dec21c: 45 frames
20sep11a: 55 frames
21jan18d: 55 frames

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Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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