EMPIAR-10868 - Cryo electron microscopy of hIAPP fibrils seeded by patient-extracted fibrils [20390 multi-frame micrographs composed of 30 frames each in TIFF format]

EMPIAR-10868

Cryo electron microscopy of hIAPP fibrils seeded by patient-extracted fibrils [20390 multi-frame micrographs composed of 30 frames each in TIFF format]

Publication:

Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores

Cao Q, Boyer DR, Sawaya MR, Abskharon R, Saelices L, Nguyen BA, Lu J, Murray KA, Kandeel F, Eisenberg DS

Nature structural & molecular biology 28 (2021) 724-730

PMID: 34518699

DOI: 10.1038/s41594-021-00646-x

Related EMDB entry:

EMD-23688 EMD-23689 EMD-23686 EMD-23687

Deposited:

2021-11-09

Released:

2021-11-26

Last modified:

2021-11-26

Imageset size:

9.94 TB

Imageset DOI:

10.6019/EMPIAR-10868

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned K3 movies of hIAPP fibrils seeded by disease fibrils

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

20390

Image size:

(11520, 8184)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.533, 0.533)

Details:

Data collected in two sessions (January and August). Each has their own gain file.

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)