EMPIAR-10768
Single particle cryo-EM dataset of sarkosyl-insoluble fraction from the nucleus accumbens of an individual with argyrophilic grain disease [15227 multi-frame micrographs composed of 35 frames each in TIFF format]
Publication:

Structure-based classification of tauopathies

Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW

Nature 598 (2021) 359-363

PMID: 34588692

Related EMDB entry:
Deposited:
2021-07-17
Released:
2021-09-17
Last modified:
2021-10-19
Imageset size:
2.84 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame movies
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
15227
Image size:
(5760, 4092)
Pixel type:
UNSIGNED BYTE
Pixel spacing:
(1.17, 1.17)
Details:
The files were written as gain-unnormalised TIF files by EPU. The dose rate is 0.89 e/A2/frame. Please use Movies/FoilHole_19945800_Data_19967971_19967973_20210320_192134_gain.tiff as a gain reference without any rotation or flipping.

data/AGD/start_end_coordinates contains start-end coordinates of the manually picked filaments.

data/AGD/data.star contains STAR files with the metadata of the final refined segments.
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Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y. (2023)
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