EMPIAR-10736
Cryo-EM of the human insulin receptor ectodomain in complex with an insulin analog with truncated B chain and enlongated A chain [multiple data sets in MRC format]
Publication:

Symmetric and asymmetric receptor conformation continuum induced by a new insulin

Forbes BE, Safavi-Hemami H, Hill CP, Chou DH

Nature chemical biology 18 (2022) 511-519

PMID: 35289328

Related EMDB entry:
Deposited:
2021-05-12
Released:
2022-03-14
Last modified:
2022-09-15
Imageset size:
2.20 TB
Imageset DOI:
Experimental metadata:
Download xml json

Compressed by PDBj:

Image formats and pixel types shown below are those of the original, non-compressed files.

Movies in this entry were compressed to TIFF by EMPIAR Japan to save space and bandwidth.
The compression is lossless in that all pixel intensities remain exactly the same after decompression.
However, some metadata in the MRC header were lost.
The original files before compression are available from EMPIAR EBI.

The following three files were found corrupted and removed.

- movies-dose-60/FoilHole_22055695_Data_22053810_22053812_20191121_2111-86724.mrc
- movies-dose-60/FoilHole_22055696_Data_22053772_22053774_20191121_2113-86730.mrc
- movies-dose-60/FoilHole_22055696_Data_22053778_22053780_20191121_2113-86731.mrc

Original size:   12,569,361,786 kilobytes
Compressed size:  2,357,786,229 kilobytes
Contains:
  • micrographs - multiframe
1. Unaligned multi-frame micrographs (40 e-/A2 dose)
Category:
micrographs - multiframe
Image format:
MRC
No. of images or tilt series:
7221
Image size:
(3838, 3710)
Pixel type:
UNSIGNED 16 BIT INTEGER
Pixel spacing:
(1.365, 1.365)
Details:
Raw, uncurated cryo-EM movies. Not gain corrected. Use gain image matching pattern *-gain-ref.mrc
Files:
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2. unaligned micrographs (60 e-/A2 dose)
Category:
micrographs - multiframe
Image format:
MRC
No. of images or tilt series:
4078
Image size:
(3838, 3710)
Pixel type:
UNSIGNED 16 BIT INTEGER
Pixel spacing:
(1.365, 1.365)
Details:
Raw, uncurated cryo-EM movies. Not gain corrected. Use gain image matching pattern *-gain-ref.mrc
Files:
Loading...
Files:
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Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva A, Zhou ZH, Chen XS. (2023)
Rigden DJ, Fernández XM. (2023)
Iudin A, Korir PK, Somasundharam S, Weyand S, Cattavitello C, Fonseca N, Salih O, Kleywegt GJ, Patwardhan A. (2023)
Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y. (2023)
Caldwell BJ, Norris AS, Karbowski CF, Wiegand AM, Wysocki VH, Bell CE. (2022)