EMPIAR-10648 - PKM2 in complex with Compound 5 [707 multi-frame micrographs composed of 60 frames each in TIFF format]

EMPIAR-10648

PKM2 in complex with Compound 5 [707 multi-frame micrographs composed of 60 frames each in TIFF format]

Publication:

Fragment-based drug discovery using cryo-EM

Saur M, Hartshorn MJ, Dong J, Reeks J, Bunkoczi G, Jhoti H, Williams PA

Drug discovery today (2019)

PMID: 31877353

DOI: 10.1016/j.drudis.2019.12.006

Related EMDB entry:

EMD-10575

Deposited:

2021-02-23

Released:

2021-03-12

Last modified:

2021-03-12

Imageset size:

773.77 GB

Imageset DOI:

10.6019/EMPIAR-10648

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Data from EPU (movies have been converted to compressed TIF)

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

707

Image size:

(4096, 4096)

Pixel type:

UNSIGNED 16 BIT INTEGER

Pixel spacing:

(0.752, 0.752)

Details:

This dataset provides the 'Data' folder inside Images-Disc1/GridSquare..../ folders. The movies have been converted to compressed TIF files to safe space using relion_convert_to_tiff. Standard values have been used for conversion, i.e. compression is zip level 6.

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Citations

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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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