EMPIAR-10594
Human NLRP1-DPP9 complex [multiple data sets in TIFF format]
Publication:

DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation

Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H

Nature (2021)

PMID: 33731932

Related EMDB entry:
Deposited:
2020-06-17
Released:
2021-04-14
Last modified:
2021-04-14
Imageset size:
2.30 TB
Imageset DOI:
Experimental metadata:
Download xml json
Contains:
  • micrographs - multiframe
1. Unaligned multi frame micographs of NLRP1-DPP9-Apo-noTILT dataset
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
7836
Image size:
(None, None)
Pixel type:
BIT
Pixel spacing:
(0.825, 0.825)
Details:
Dataset of NLRP1-DPP9-apo complex with zero TILT data
The defocus range between −1 to −2.5 μm and to record two shots for each of the four
holes per stage movement through image shift. All movies were exposed with a total dose of 67.5
e-/Å2 for 1.8 s fractionated over 45 frames
Files:
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2. Unaligned multi frame micographs of NLRP1-DPP9-Apo-TILT dataset
Category:
micrographs - multiframe
Image format:
TIFF
No. of images or tilt series:
1924
Image size:
(None, None)
Pixel type:
BIT
Pixel spacing:
(0.825, 0.825)
Details:
37 degrees TILT data set of NLRP1-DPP9-apo complex.
The defocus range between −1.5 to −3.0 μm with two shots recorded for each hole per stage movement through image shift. All movies were exposed with a total dose of 67.6 e-/Å2 for 2.6 s fractionated over 45 frames.
Files:
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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)
Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)
Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)
Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)