EMPIAR-10323 - Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy [1713 micrographs in MRC format]

EMPIAR-10323

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy [1713 micrographs in MRC format]

Publication:

Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy

Guerrero-Ferreira R, Taylor NM, Arteni AA, Kumari P, Mona D, Ringler P, Britschgi M, Lauer ME, Makky A, Verasdonck J, Riek R, Melki R, Meier BH, Böckmann A, Bousset L, Stahlberg H

eLife 8 (2019)

PMID: 31815671

DOI: 10.7554/eLife.48907

Related EMDB entry:

EMD-10307 EMD-10305

Deposited:

2019-09-23

Released:

2020-03-04

Last modified:

2020-08-13

Imageset size:

90.87 GB

Imageset DOI:

10.6019/EMPIAR-10323

Experimental metadata:

Download xml json

Contains:

micrographs - single frame

Image Sets

1. Aligned micrographs of alpha-synuclein fibrils

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

1713

Image size:

(3838, 3710)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(0.6556, 0.6556)

Details:

Micrographs were drift-corrected and dose-weighted using MotionCor2. Accumulated dose of 69 electrons per square Angstrom (10 second exposure, 50 frames)

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Citations

GTpick: A deep neural network for Cryo-EM particle detection.

Ni S, Yang C, Liu Y, Zhang Y, Shi Y, Qian A, Kong R, Chang S. (2025)

High-resolution ab initio reconstruction enables cryo-EM structure determination of small particles

Kim K, Li H, Clarke OB. (2025)

CLEM-Reg: an automated point cloud-based registration algorithm for volume correlative light and electron microscopy.

Krentzel D, Elphick M, Domart MC, Peddie CJ, Laine RF, Shand C, Henriques R, Collinson LM, Jones ML. (2025)

CryoEMNet driven symmetry-aware molecular reconstruction through deep learning enhanced electron microscopy.

Arora S, Pan SH, Kumar S, Singh SK, Chauhan U, Alhalabi W, Arya V, Alsulami BS, Hsu CH, Chui KT, Gupta BB. (2025)

PERC: a suite of software tools for the curation of cryoEM data with application to simulation, modeling and machine learning.

Costa-Gomes B, Greer J, Juraschko N, Parkhurst J, Mirecka J, Famili M, Rangel-Smith C, Strickson O, Lowe A, Basham M, Burnley T. (2025)

Few-Shot Classification of Cryo-EM Micrographs Using Triplet Loss Embeddings

--- (2025)

Self-supervised learning for generalizable particle picking in cryo-EM micrographs.

Zamanos A, Koromilas P, Bouritsas G, Kastritis PL, Panagakis Y. (2025)

Conserved hydrophilic checkpoints tune FocA-mediated formate:H<sup>+</sup> symport.

Tüting C, Janson K, Kammel M, Ihling C, Lorenz J, Kyrilis FL, Hamdi F, Erdmann C, Sinz A, Sawers RG, Kastritis PL. (2025)

Icecream: High-Fidelity Equivariant Cryo-Electron Tomography

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2025)

Laser flash melting cryo-EM samples to overcome preferred orientation.

Straub MS, Harder OF, Mowry NJ, Barrass SV, Hruby J, Drabbels M, Lorenz UJ. (2025)

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