EMPIAR-10285 - Cryo-electron microscopy structure of the P-Rex1–G-beta-gamma signaling scaffold [multiple data sets in TIFF, MRC and MRCS formats]

EMPIAR-10285

Cryo-electron microscopy structure of the P-Rex1–G-beta-gamma signaling scaffold [multiple data sets in TIFF, MRC and MRCS formats]

Publication:

Cryo-electron microscopy structure and analysis of the P-Rex1-Gβγ signaling scaffold

Cash JN, Urata S, Li S, Ravala SK, Avramova LV, Shost MD, Gutkind JS, Tesmer JJG, Cianfrocco MA

Science advances 5 (2019)

PMID: 31663027

DOI: 10.1126/sciadv.aax8855

Related EMDB entry:

EMD-20308

Deposited:

2019-06-18

Released:

2019-11-19

Last modified:

2019-11-19

Imageset size:

3.00 TB

Imageset DOI:

10.6019/EMPIAR-10285

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe
micrographs - single frame
picked particles - single frame - processed

Image Sets

1. Movie files (.tif) for P-Rex1-Gbg

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

6746

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

---

Files:

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2. Micrograph files (.mrc) & CTF log files for P-Rex1-Gbg

Category:

micrographs - single frame

Image format:

MRC

No. of images or tilt series:

6736

Image size:

(None, None)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(None, None)

Details:

---

Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

3. Extracted particles from Warp for P-Rex1-Gbg

Category:

picked particles - single frame - processed

Image format:

MRCS

No. of images or tilt series:

6360

Image size:

(None, None)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(None, None)

Details:

Particle coordinate files (*.star) for P-Rex1-Gbg can be found in the directory data/matching

Files:

Archives and downloads the selected files into an uncompressed zip file.

We recommend using rsync, aspera, globus, etc.

Download a list of selected files.

It is possible to download files by specifying the file list with rsync command, etc.

rsync -av --files-from=(path-to-filelist) rsync://empiar.pdbj.org/empiar/archive (path-to-destination)

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Citations

prismPYP: Power-spectrum and image domain learning for self-supervised micrograph evaluation.

He L, Bartesaghi A. (2026)

CryoSIP: unleashing protein high-resolution Cryo-EM via semantic-instance collaborative picking.

Deng Y, Wang S, Xiang M, Li Y, Zhuo L, Cao D, Fu X, Zou Q. (2026)

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Fonseca N, Duraisamy AK, Wang Z, Somasundharam S, Tayebinia M, de Oliveira LC, Ma M, Turner J, Patwardhan A, Kleywegt GJ, Hartley M, Morris KL. (2026)

CryoVirusDB: An Annotated Dataset for AI-Based Virus Particle Identification in Cryo-EM Micrographs.

Gyawali R, Dhakal A, Wang L, Cheng J. (2026)

Deep-learning methods for contrast enhancement and artifact reduction in cryo-electron tomography: a systematic analysis of the state of the art and proposed improvements.

Jones HN, Deshmukh A, Pande K. (2026)

CryoGS: High-Quality Cryo-EM Homogeneous Reconstruction by Gaussian Splatting

Zeng B, Liu S, Cheng S, Xu G, Fan H. (2026)

Point cloud deformation modeling for particle selection following cryo-EM 2D classification.

Wang X, Mo Z, Li F, Zhang F, Wan X. (2026)

ICECREAM: high-fidelity equivariant cryo-electron tomography.

Kishore V, Debarnot V, Righetto RD, Engel BD, Dokmanić I. (2026)

CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection.

Schäfer JH, Calza A, Hom K, Damodar P, Peng R, Bogdanović N, Lander GC, Stagg SM, Cianfrocco MA. (2025)