EMPIAR-12091 - In situ cryoET of beta-amyloid and tau in post-mortem Alzheimer's disease brain [61 reconstructed volumes in MRC format]

EMPIAR-12091

In situ cryoET of beta-amyloid and tau in post-mortem Alzheimer's disease brain [61 reconstructed volumes in MRC format]

Publication:

CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain

Gilbert MAG, Fatima N, Jenkins J, O'Sullivan TJ, Schertel A, Halfon Y, Wilkinson M, Morrema THJ, Geibel M, Read RJ, Ranson NA, Radford SE, Hoozemans JJM, Frank RAW

Nature (2024)

PMID: 38987603

DOI: 10.1038/s41586-024-07680-x

Related EMDB entry:

EMD-50155 EMD-50159 EMD-50156 EMD-50157 EMD-50161 EMD-50153 EMD-50148 EMD-50160 EMD-50162 EMD-50152

Deposited:

2024-05-20

Released:

2024-07-16

Last modified:

2024-07-16

Imageset size:

166.99 GB

Imageset DOI:

10.6019/EMPIAR-12091

Experimental metadata:

Download xml json

Contains:

reconstructed volumes

Image Sets

1. Liftout lamella and cryo-section tomograms of post-mortem AD brain tissue

Category:

reconstructed volumes

Image format:

MRC

No. of images or tilt series:

Image size:

(1024, 1024)

Pixel type:

32 BIT FLOAT

Pixel spacing:

(9.6, 9.6)

Details:

Liftout lamella and cryo-section tomograms of post-mortem AD brain tissue

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Citations

Small LEA proteins mitigate air-water interface damage to fragile cryo-EM samples during plunge freezing.

Abe KM, Li G, He Q, Grant T, Lim CJ. (2024)

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Fenn KL, Horne JE, Crossley JA, Böhringer N, Horne RJ, Schäberle TF, Calabrese AN, Radford SE, Ranson NA. (2024)

Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.

Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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