EMPIAR-11318 - Tau filaments from the cellular fraction of Alzheimer's disease patient brain [12117 multi-frame micrographs composed of 40 frames each in TIFF format]

EMPIAR-11318

Tau filaments from the cellular fraction of Alzheimer's disease patient brain [12117 multi-frame micrographs composed of 40 frames each in TIFF format]

Publication:

Tau filaments are tethered within brain extracellular vesicles in Alzheimer’s disease

Fowler SL, Behr TS, Turkes E, Cauhy PM, Foiani MS, Schaler A, Crowley G, Bez S, Ficulle E, Tsefou E, O’Brien DP, Fischer R, Geary B, Gaur P, Miller C, D’Acunzo P, Levy E, Duff KE, Ryskeldi-Falcon B

bioRxiv (2023)

DOI: 10.1101/2023.04.30.537820

Related EMDB entry:

EMD-16039

Deposited:

2022-11-11

Released:

2023-11-07

Last modified:

2023-11-07

Imageset size:

1.94 TB

Imageset DOI:

10.6019/EMPIAR-11318

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned multiframe movies

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

12117

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(0.834, 0.834)

Details:

The files were written as gain-unnormalised integer MRC files by EPU and then converted to TIFF files by mrc2tif in the IMOD suite. During this process, the pixel size in the header was lost. The real pixel size is 0.834 Å/px. The dose rate is 0.89 e/Å2/frame. The files were collected in two sessions, with separate gain references. Please use the corresponding gain.tiff files a gain reference without any rotation or flipping.

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