EMPIAR-10247 - TRPV2 ion channel gating through allosteric domain coupling revealed by cryo-EM [1969 multi-frame micrographs composed of 35 frames each in MRCS format]

EMPIAR-10247

TRPV2 ion channel gating through allosteric domain coupling revealed by cryo-EM [1969 multi-frame micrographs composed of 35 frames each in MRCS format]

Publication:

Structures of TRPV2 in distinct conformations provide insight into role of the pore turret

Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W

Nature structural & molecular biology 26 (2018) 40-49

PMID: 30598551

DOI: 10.1038/s41594-018-0168-8

Related EMDB entry:

EMD-7118

Deposited:

2019-01-07

Released:

2019-07-25

Last modified:

2019-07-25

Imageset size:

3.57 TB

Imageset DOI:

10.6019/EMPIAR-10247

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. TRPV2 WT with pore turret domain

Category:

micrographs - multiframe

Image format:

MRCS

No. of images or tilt series:

1969

Image size:

(None, None)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(None, None)

Details:

---

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The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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