EMPIAR-12331 - EcPKS2 inhibited with Malonyl-CoA [17420 multi-frame micrographs composed of 50 frames each in TIFF format]

EMPIAR-12331

EcPKS2 inhibited with Malonyl-CoA [17420 multi-frame micrographs composed of 50 frames each in TIFF format]

Publication:

The structure of full-length AFPK supports the ACP linker in a role that regulates iterative polyketide and fatty acid assembly

Schubert HL, Li F, Hill CP, Schmidt EW

Proceedings of the National Academy of Sciences of the United States of America 122 (2025)

PMID: 39913209

DOI: 10.1073/pnas.2419884122

Related EMDB entry:

EMD-45907 EMD-45909 EMD-45910

Deposited:

2024-10-08

Released:

2025-02-27

Last modified:

2025-02-27

Imageset size:

4.57 TB

Imageset DOI:

10.6019/EMPIAR-12331

Experimental metadata:

Download xml json

Contains:

micrographs - multiframe

Image Sets

1. Unaligned frames for EcPKS2 inhibited with Malonyl-CoA showing the ACP domain at the KS activesite

Category:

micrographs - multiframe

Image format:

TIFF

No. of images or tilt series:

17420

Image size:

(5760, 4092)

Pixel type:

UNSIGNED BYTE

Pixel spacing:

(1.06, 1.06)

Details:

---

Files:

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Citations

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Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

Kofler L, Grundmann L, Gerhalter M, Prattes M, Merl-Pham J, Zisser G, Grishkovskaya I, Hodirnau VV, Vareka M, Breinbauer R, Hauck SM, Haselbach D, Bergler H. (2024)

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