EMPIAR-12082 - In situ cryoET of beta-amyloid and tau in post-mortem Alzheimer's disease brain [61 tilt series in MRC format]

EMPIAR-12082

In situ cryoET of beta-amyloid and tau in post-mortem Alzheimer's disease brain [61 tilt series in MRC format]

Publication:

CryoET of β-amyloid and tau within postmortem Alzheimer's disease brain

Gilbert MAG, Fatima N, Jenkins J, O'Sullivan TJ, Schertel A, Halfon Y, Wilkinson M, Morrema THJ, Geibel M, Read RJ, Ranson NA, Radford SE, Hoozemans JJM, Frank RAW

Nature (2024)

PMID: 38987603

DOI: 10.1038/s41586-024-07680-x

Related EMDB entry:

EMD-50155 EMD-50159 EMD-50156 EMD-50157 EMD-50161 EMD-50153 EMD-50148 EMD-50160 EMD-50162 EMD-50152

Deposited:

2024-04-22

Released:

2024-07-16

Last modified:

2024-07-16

Imageset size:

149.37 GB

Imageset DOI:

10.6019/EMPIAR-12082

Experimental metadata:

Download xml json

Contains:

tilt series

Image Sets

1. Dose fractionated movie frames and tomograms for CS1-CS7 and LOL1-2

Category:

tilt series

Image format:

MRC

No. of images or tilt series:

Image size:

(4096, 4096)

Pixel type:

SIGNED 16 BIT INTEGER

Pixel spacing:

(2.4, 2.4)

Details:

Dose fractionated movie frames and tomograms for CS1-CS7 and LOL1-2

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Hicks CW, Rahman S, Gloor SL, Fields JK, Husby NL, Vaidya A, Maier KE, Morgan M, Keogh MC, Wolberger C. (2024)

Molecular recognition of an odorant by the murine trace amine-associated receptor TAAR7f.

Gusach A, Lee Y, Khoshgrudi AN, Mukhaleva E, Ma N, Koers EJ, Chen Q, Edwards PC, Huang F, Kim J, Mancia F, Veprintsev DB, Vaidehi N, Weyand SN, Tate CG. (2024)

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation.

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